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A lethal cancer’s long reach

January 1, 2023

Ovarian cancer is notoriously difficult to detect. Here’s how to arm yourself against this silent killer.

photo of a woman talking with her doctor; the image is cropped so only their torsos and hands are visible

Dr. Katharine Esselen vividly recalls one of her most tragic cases. A woman in her 50s showed up with a hallmark sign of ovarian cancer — a bloated belly. Quickly, Dr. Esselen and her colleagues confirmed the diagnosis, learning the woman had mentioned this and other symptoms to her primary care doctor elsewhere in the past. But her doctor never asked about any family history of the disease — a glaring omission, since the woman’s mother had died of ovarian cancer in her 30s.

"This was a super-fit and energetic woman who’d been good about getting care, and it broke my heart because we diagnosed her when she was incurable," recalls Dr. Esselen, a gynecologic oncologist at Harvard-affiliated Beth Israel Deaconess Medical Center. "It was such a missed opportunity to refer her for genetic counseling or testing," along with tests that may have led to earlier diagnosis.

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About the Author

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Maureen Salamon, Executive Editor, Harvard Women's Health Watch

Maureen Salamon is executive editor of Harvard Women’s Health Watch. She began her career as a newspaper reporter and later covered health and medicine for a wide variety of websites, magazines, and hospitals. Her work has … See Full Bio
View all posts by Maureen Salamon

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