Prostate Cancer Archive

Prostate-specific antigen (PSA) screening can help identify early prostate cancer, but it also can lead men to have biopsies and invasive treatments they may not need. This complexity has caused the medical community to re-evaluate how best to use PSA testing. More doctors are using PSA screening in ways that minimize the use of biopsies, such as by following a worrisome test result with MRI of the prostate. If a man does have a biopsy and a cancer is found, PSA testing can help the man follow active surveillance.

In some men with localized prostate cancer, focal therapy is an alternative to radical prostatectomy. This procedure removes only the cancerous part of the gland, and growing evidence shows it can be an effective strategy.

Eating a plant-based diet like the Mediterranean, MIND, or DASH diet has been shown to help people lose weight and lower their risk for heart disease and diabetes. But such a diet may also help men lower their risk for prostate cancer or help slow the spread of existing prostate cancer. The connection may be due to high consumption of inflammation-fighting fruits, vegetables, and fatty fish, and the fact that people who follow a plant-based diet eat less red meat and processed foods, high intakes of which are associated with cancer risk.

Approval by the FDA of a new drug combination for treatment of advanced prostate cancer fills a need and offers new hope to men whose cancer has progressed and who have already tried other therapies.

Guidelines recommend against routine prostate-specific antigen (PSA) testing in men ages 70 and older. Still, two 2023 studies found that men in this age group are having too many PSA tests.

In general, prostate cancer that occurs after age 60 does not increase the risk of getting a second, different cancer. However, lifestyle habits that contribute to prostate cancer, like poor diet, lack of exercise, and obesity, can raise the risk for other cancers.

Prostate cancer is generally viewed as a disease of older men, yet about 10% of new diagnoses occur in men age 55 or younger. Biological differences partially explain the discrepancy, but socioeconomic factors also play an important role.

Men who are diagnosed with certain types of prostate cancer often choose active surveillance, which allows them to delay the need for aggressive treatment. The results of a long-term study affirm that this approach is a valid option for managing the disease.

Men with low-risk prostate cancer continue to choose active surveillance as their course of action, meaning they monitor their cancer and don’t seek treatment unless it becomes worse. While this wait-and-see approach may appear passive in nature, it’s an opportunity for men to take charge of their health and make lifestyle changes that could improve their cancer outcome and offer protection against other health risks, like heart disease.

The increasing size and visibility of the transgender population has implications for public health. Hormone treatment given to transgender women lowers the overall risk of prostate cancer, but the risk of a trans woman developing the disease is not zero.