Colorectal Cancer Archive

In 2024, the FDA approved a blood test called Shield as a screening method for colorectal cancer. The test detects 83% of colorectal cancers, but only 13% of precancerous polyps. The FDA approval means that now many insurance plans will pay for the test.

Of the cancer screening tests for men, tests for colon cancer has the strongest evidence for benefit. Men who opt in for prostate cancer screening may have more options beyond PSA blood testing to more accurately identify aggressive cancers. Other screening tests such as full body scans have not been shown to improve outcomes.

Screening methods for colorectal cancer continue to evolve. Stool tests are becoming more accurate, and it appears that an experimental blood test might one day provide another effective screening option. The most accurate colorectal cancer screening is a colonoscopy, which allows a doctor to peer inside the colon and rectum, find cancers, and remove potentially precancerous polyps on the spot to prevent future cancer. It's unclear if a stool or blood test will ever be as good for screening as a colonoscopy.

A 2023 study suggests that having diabetes may be tied to a higher risk of developing colorectal cancer than not having diabetes.

Lynch syndrome is an inherited condition that predisposes people to colorectal, uterine, ovarian, and other forms of cancer. Genetic testing can pinpoint Lynch syndrome, and genetic counseling is also recommended. People with Lynch syndrome need frequent cancer screenings and should watch for symptoms. Women with Lynch syndrome are also advised to undergo risk-reducing surgery that removes the ovaries, fallopian tubes, and uterus between ages 35 and 40, unless a woman is planning another pregnancy.

According to a 2023 observational study, greater cardiorespiratory fitness in men was linked to a lower risk of death from colon, lung, or prostate cancer.

In the US population as a whole, deaths from colon cancer have been declining, but in people under 50 that rate has increased. Most major medical organizations recommend screening beginning at age 45 for people at average risk.

A 2022 study led to questions regarding whether colonoscopy is the best strategy to reduce the risk of death from colon cancer. But overwhelming evidence supports the procedure for lowering the risk of colon cancer and related death, and experts continue to recommend people at average risk get at least one colonoscopy beginning at age 45.