Prebiotics in plant-based foods may help control unhealthy eating

In the journals

By , Executive Editor, Harvard Men's Health Watch


Science has shown that a healthy gut can make beneficial changes in the brain and vice versa, via a connection known as the gut-brain axis. A healthy gut requires good amounts of probiotics (beneficial bacteria), which grow by feeding off prebiotics, compounds found in plant fiber. A new study suggests prebiotics have a role in the gut-brain axis beyond being a food source and eating them might help people choose healthier foods.

Researchers recruited 59 overweight adults who regularly followed a Western diet (higher in red meat, saturated fat, and processed foods) and assigned them randomly to take either 30 grams of inulin (a prebiotic found in onions, leeks, artichokes, and bananas) or a placebo supplement, every day for two weeks. Next, the participants had brain MRIs while they viewed pictures of various low-, medium-, and high-calorie foods and indicated how much they wanted them on a one to 10 scale. The MRIs measured how much of the brain's reward network was activated when the participants made their choices. Over a second two-week period, the process was repeated: everyone took the supplement they had not taken earlier, and then underwent the MRI session. The researchers found that after taking the prebiotic supplement, people were more likely to select medium- or low-calorie foods than high-calorie ones, and their MRIs showed less activation in their brain's reward network when shown high-calorie foods.

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About the Author

photo of Matthew Solan

Matthew Solan, Executive Editor, Harvard Men's Health Watch

Matthew Solan is the executive editor of Harvard Men’s Health Watch. He previously served as executive editor for UCLA Health’s Healthy Years and as a contributor to Duke Medicine’s Health News and Weill Cornell Medical College’s … See Full Bio
View all posts by Matthew Solan

About the Reviewer

photo of Howard E. LeWine, MD

Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing

Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio
View all posts by Howard E. LeWine, MD


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