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Heart Health
Stroke prevention in atrial fibrillation: Beyond anti-clotting drugs
- By Julie Corliss, Executive Editor, Harvard Heart Letter
Procedures that block or remove the source of dangerous blood clots in the heart may be an option for growing numbers of people.
More than five million Americans have atrial fibrillation, a heart rhythm disorder commonly known as afib. During a bout of afib, the heart’s upper chambers (atria) suddenly start to quiver ineffectually. When that happens, blood tends to pool — and possibly form clots — in a small pouch that protrudes from the top of the left atrium. This ear-shaped sac is called the left atrial appendage (LAA).
About 90% of blood clots in the heart form in the LAA. These clots can escape the heart and travel to the brain, blocking blood flow and causing an ischemic stroke. Most people with afib take anti-clotting medications that help prevent these strokes. However, some people develop serious bleeding problems while taking those medications. Also known as blood thinners, these drugs are especially risky for older people who are vulnerable to head injuries from falls, increasing the risk of bleeding in and around the brain.
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About the Author

Julie Corliss, Executive Editor, Harvard Heart Letter
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
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Managing Atrial Fibrillation
Managing Atrial Fibrillation will explain what atrial fibrillation is, how to know if you have it, its causes, and the treatments available. Afib can be a complex health condition, so the more you know about it, the better you will be able to work with your doctor. If afib is monitored and treated correctly, you can minimize its symptoms and help to prevent serious complications like stroke and heart damage.
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